Functions of estrogens and anti‐estrogens in the rat endometrial adenocarcinoma cell lines RUCA‐I and RUCA‐II

@article{Schtze1992FunctionsOE,
  title={Functions of estrogens and anti‐estrogens in the rat endometrial adenocarcinoma cell lines RUCA‐I and RUCA‐II},
  author={N. Sch{\"u}tze and V. Kraft and F. Deerberg and H. Winking and D. Meitinger and K. Ebert and R. Knuppen and G. Vollmer},
  journal={International Journal of Cancer},
  year={1992},
  volume={52}
}
Inbred rats of the DA/Han and BDII/Han strains have been proposed as suitable model systems for studying hormonal carcinogenesis, because they die mainly from hormone‐dependent endometrial adenocarcinoma. Here we characterize the RUCA‐I cell line derived from an endometrial adenocarcinoma of an inbred DA/ Han rat and the RUCA‐II cell line derived from an endometrial adenocarcinoma of an inbred BDII/Han rat. The RUCA‐I cell line, if transplanted to the neck of female DA/ Han rats, gives rise to… Expand
The rat endometrial adenocarcinoma cell line RUCA-I: a novel hormone-responsive in vivol/in vitro tumor model
Estrogen-dependent and cell-specific regulation of gene expression in RUCA-I endometrial adenocarcinoma cells
Endometrial cancer: experimental models useful for studies on molecular aspects of endometrial cancer and carcinogenesis.
  • G. Vollmer
  • Biology, Medicine
  • Endocrine-related cancer
  • 2003
Fibronectin is an estrogen-repressed protein in RUCA-I rat endometrial adenocarcinoma cells
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