Functions of diacylglycerol in glycerolipid metabolism, signal transduction and cellular transformation.

@article{Bishop1988FunctionsOD,
  title={Functions of diacylglycerol in glycerolipid metabolism, signal transduction and cellular transformation.},
  author={W. Robert Bishop and R M Bell},
  journal={Oncogene research},
  year={1988},
  volume={2 3},
  pages={205-18}
}
Clearly, cellular DAG levels are regulated at the levels of synthesis, degradation and compartmentalization. This complex regulation enables DAG to perform its two distinct roles: supporting the biosynthesis (and degradation) of glycerolipids, and regulating PKC activity. Further definition is needed as to how DAG fulfills both functions, with particular emphasis on how distinct DAG pools are maintained, the interrelationships between the numerous pathways of DAG metabolism, and the role which… CONTINUE READING
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