Functions of coenzyme Q10 in inflammation and gene expression.

  title={Functions of coenzyme Q10 in inflammation and gene expression.},
  author={Constance Schmelzer and Inka Lindner and Gerald H. Rimbach and Petra Niklowitz and Thomas Menke and Frank D{\"o}ring},
  volume={32 1-4},
Clinical studies demonstrated the efficacy of Coenzyme Q10 (CoQ10) as an adjuvant therapeutic in cardiovascular diseases, mitochondrial myopathies and neurodegenerative diseases. More recently, expression profiling revealed that Coenzyme Q10 (CoQ10) influences the expression of several hundred genes. To unravel the functional connections of these genes, we performed a text mining approach using the Genomatix BiblioSphere. We identified signalling pathways of G-protein coupled receptors, JAK… CONTINUE READING


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