Functions of a jumonji-cyclin D1 pathway in the coordination of cell cycle exit and migration during neurogenesis in the mouse hindbrain.

@article{Takahashi2007FunctionsOA,
  title={Functions of a jumonji-cyclin D1 pathway in the coordination of cell cycle exit and migration during neurogenesis in the mouse hindbrain.},
  author={Miho Takahashi and Mizuyo Kojima and Kuniko Nakajima and Rika Suzuki-Migishima and Takashi Takeuchi},
  journal={Developmental biology},
  year={2007},
  volume={303 2},
  pages={549-60}
}
During development of the mouse central nervous system (CNS), most neural progenitor cells proliferate in the ventricular zone (VZ). In many regions of the CNS, neural progenitor cells give rise to postmitotic neurons that initiate neuronal differentiation and migrate out of the VZ to the mantle zone (MZ). Thereafter, they remain in a quiescent state. Here, we found many ectopic mitotic cells and cell clusters expressing neural progenitor or proneural marker genes in the MZ of the hindbrain of… CONTINUE READING

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