Functions of SK channels in central neurons.

  title={Functions of SK channels in central neurons.},
  author={E. S. Louise Faber and P. H. Balaji Sah},
  journal={Clinical and experimental pharmacology & physiology},
  volume={34 10},
1. SK channels are small-conductance calcium-activated potassium channels that are widely expressed in neurons. The traditional view of the functional role of SK channels is in mediating one component of the after-hyperpolarization that follows action potentials. Calcium influx via voltage-gated calcium channels active during action potentials opens SK channels and the resultant hyperpolarization lowers the firing frequency of action potentials in many neurons. 2. Recent advances have shown… CONTINUE READING
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