Functions of PIWI proteins in spermatogenesis

  title={Functions of PIWI proteins in spermatogenesis},
  author={Chong Won Bak and Tae-Ki Yoon and Youngsok Choi},
  booktitle={Clinical and experimental reproductive medicine},
Recently, a significant understanding of the molecular mechanisms regulating spermatogenesis has been achieved utilizing small RNA molecules (small RNAs), including small interfering RNAs (siRNAs), microRNAs (miRNAs), and Piwi-interacting RNAs (piRNAs) which emerged as important regulators of gene expression at the post-transcriptional or translation level. piRNAs are only present in pachytene spermatocytes and round spermatids, whereas miRNAs are expressed abundantly in male germ cells… CONTINUE READING
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