Functions of Lsm proteins in mRNA degradation and splicing.

  title={Functions of Lsm proteins in mRNA degradation and splicing.},
  author={Weihai He and Roy Parker},
  journal={Current opinion in cell biology},
  volume={12 3},
Recent results have identified a family of Lsm (Like Sm) proteins that are related to the Sm protein family. Seven Lsm proteins form a complex, which interacts with the U6 snRNA and functions in splicing. In addition, a different complex of Lsm proteins interacts with cytoplasmic mRNA and promotes its turnover. These diverse functions of Lsm proteins suggest that they are important modulators of RNA biogenesis and function. 

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