Functions of Fyn kinase in the completion of meiosis in mouse oocytes.

Abstract

Oocyte maturation invokes complex signaling pathways to achieve cytoplasmic and nuclear competencies for fertilization and development. The Src-family kinases FYN, YES and SRC are expressed in mammalian oocytes but their function during oocyte maturation remains an open question. Using chemical inhibitor, siRNA knockdown, and gene deletion strategies the… (More)
DOI: 10.1016/j.ydbio.2008.11.038

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