Functionally separate intracellular Ca2+ stores in smooth muscle.

@article{Flynn2001FunctionallySI,
  title={Functionally separate intracellular Ca2+ stores in smooth muscle.},
  author={Elaine R M Flynn and Karen N. Bradley and Thomas C. Muir and John G. McCarron},
  journal={The Journal of biological chemistry},
  year={2001},
  volume={276 39},
  pages={36411-8}
}
In smooth muscle, release via the inositol 1,4,5-trisphosphate (Ins(1,4,5)P(3)R) and ryanodine receptors (RyR) on the sarcoplasmic reticulum (SR) controls oscillatory and steady-state cytosolic Ca(2+) concentrations ([Ca(2+)](c)). The interplay between the two receptors, itself determined by their organization on the SR, establishes the time course and spatial arrangement of the Ca(2+) signal. Whether or not the receptors are co-localized or distanced from each other on the same store or… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 30 extracted citations

Temporal and spatial dynamics underlying capacitative calcium entry in human colonic smooth muscle.

American journal of physiology. Gastrointestinal and liver physiology • 2008
View 4 Excerpts
Highly Influenced

Two-step Ca2+ intracellular release underlies excitation-contraction coupling in mouse urinary bladder myocytes.

American journal of physiology. Cell physiology • 2006
View 16 Excerpts
Highly Influenced

Characterization of intracellular Ca(2+) stores in gallbladder smooth muscle.

American journal of physiology. Gastrointestinal and liver physiology • 2005
View 5 Excerpts
Highly Influenced

Inositol trisphosphate receptors in smooth muscle cells.

American journal of physiology. Heart and circulatory physiology • 2012
View 3 Excerpts

Similar Papers

Loading similar papers…