Functionally related transcripts have common RNA motifs for specific RNA-binding proteins in trypanosomes

@article{No2008FunctionallyRT,
  title={Functionally related transcripts have common RNA motifs for specific RNA-binding proteins in trypanosomes},
  author={Griselda No{\'e} and Javier G. De Gaudenzi and Alberto Carlos C Frasch},
  journal={BMC Molecular Biology},
  year={2008},
  volume={9},
  pages={107 - 107}
}
Trypanosomes mostly control gene expression by post-transcriptional events such as modulation of mRNA stability and translational efficiency. These mechanisms involve RNA-binding proteins (RBPs), which associate with transcripts to form messenger ribonucleoprotein (mRNP) complexes. In this study, we report the identification of mRNA targets for Trypanosoma cruzi U-rich RBP 1 (Tc UBP1) and T. cruzi RBP 3 (Tc RBP3), two phylogenetically conserved proteins among Kinetoplastids. Co… CONTINUE READING