Functionally distinct receptors for cholecystokinin and gastrin on dispersed chief cells from guinea pig stomach.

@article{Cherner1988FunctionallyDR,
  title={Functionally distinct receptors for cholecystokinin and gastrin on dispersed chief cells from guinea pig stomach.},
  author={J A Cherner and V E Sutliff and D M Grybowski and Robert Thomas Jensen and Jerry Gardner},
  journal={The American journal of physiology},
  year={1988},
  volume={254 2 Pt 1},
  pages={G151-5}
}
Caerulein, gastrin, and C-terminal fragments of cholecystokinin (CCK) varying in length from eight (CCK-8) to four (CCK-4) amino acids stimulate pepsinogen secretion from dispersed chief cells prepared from guinea pig stomach. C-terminal fragments of CCK containing fewer than four amino acids, even when tested at concentrations as high as 3 mM, do not stimulate pepsinogen secretion. The efficacies of gastrin and the various CCK-related peptides, coupled with the pattern of action of CCK… CONTINUE READING