Functionally distinct dopamine and octopamine transporters in the CNS of the cabbage looper moth.

@article{Gallant2003FunctionallyDD,
  title={Functionally distinct dopamine and octopamine transporters in the CNS of the cabbage looper moth.},
  author={Pamela Gallant and Tabita Malutan and Heather McLean and LouAnn Verellen and Stanley Caveney and Cam Donly},
  journal={European journal of biochemistry},
  year={2003},
  volume={270 4},
  pages={
          664-74
        }
}
A cDNA was cloned from the cabbage looper Trichoplusia ni based on similarity to other cloned dopamine transporters (DATs). The total nucleotide sequence is 3.8 kb in length and contains an open reading frame for a protein of 612 amino acids. The predicted moth DAT protein (TrnDAT) has greatest amino acid sequence identity with Drosophila melanogasterDAT (73%) and Caenorhabditis elegansDAT (51%). TrnDAT shares only 45% amino acid sequence identity with an octopamine transporter (TrnOAT) cloned… CONTINUE READING

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