Functionalized hydrogel surfaces for the patterning of multiple biomolecules.

  title={Functionalized hydrogel surfaces for the patterning of multiple biomolecules.},
  author={Matthew R. Hynd and John P Frampton and Mac Burnham and David L. Martin and Natalie M. Dowell-Mesfin and James N. Turner and William Shain},
  journal={Journal of biomedical materials research. Part A},
  volume={81 2},
Patterning of multiple proteins and enzymes onto biocompatible surfaces can provide multiple signals to control cell attachment and growth. Acrylamide-based hydrogels were photo-polymerized in the presence of streptavidin-acrylamide, resulting in planar gel surfaces functionalized with the streptavidin protein. This surface was capable of binding biotin-labeled biomolecules. The proteins fibronectin and laminin, the enzyme alkaline phosphatase, and the photo-protein R-phycoerythrin were… CONTINUE READING

Similar Papers

Loading similar papers…