Functionalized graphene oxide as nanocarrier for loading and delivery of ellagic Acid.

@article{Kakran2011FunctionalizedGO,
  title={Functionalized graphene oxide as nanocarrier for loading and delivery of ellagic Acid.},
  author={Mitali Kakran and Nanda Gopal Sahoo and Haihong Bao and Ya-Ya Pan and Lin Li},
  journal={Current medicinal chemistry},
  year={2011},
  volume={18 29},
  pages={
          4503-12
        }
}
In this research, we have covalently functionalized graphene oxide (GO) with hydrophilic and biocompatible Pluronic F38 (F38), Tween 80 (T80) and maltodextrin (MD) for loading and delivery of a poorly water soluble antioxidant and anticancer drug, ellagic acid (EA). The functionalized GO showed a good aqueous solubility and biocompatibility. This is the first time that the EA was loaded onto GO-F38, GO-T80 and GO-MD through π-π interactions, yielding a loading capacity of 1 g, 1.22 g and 1.14 g… CONTINUE READING
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