Functionalized Ozonides by Substitution Reactions of Chlorinated Ozonides with Difunctional Alcohols

@inproceedings{Griesbaum1997FunctionalizedOB,
  title={Functionalized Ozonides by Substitution Reactions of Chlorinated Ozonides with Difunctional Alcohols},
  author={Karl Griesbaum and Ralf-Olaf Quinkert},
  year={1997}
}
Substitution of 3-chloro-3,5-bis(chloromethyl)-5-methyl-1,2,4-trioxolane (3) with allyl alcohol gave the corresponding diastereomeric allyloxy-substituted ozonides 4, which were converted into diozonides 7 by ozone treatment. Substitutions of 3 with ethanediol or with 1,3-propanediol gave the corresponding hydroxyalkoxy-substituted ozonides 8, 14, which were oxidized to the corresponding aldehydes 10, 16. Reaction of 3,5-dichloro-3,5-bis(chloromethyl)-1,2,4-trioxolane (1a) with ethanediol gave… CONTINUE READING

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