Functional variation in the androgen-receptor gene is associated with visceral adiposity and blood pressure in male adolescents.

@article{Pausova2010FunctionalVI,
  title={Functional variation in the androgen-receptor gene is associated with visceral adiposity and blood pressure in male adolescents.},
  author={Zdenka Pausova and Michal Abrahamowicz and Amel Mahboubi and Catriona Syme and Gabriel T. Leonard and Michel Perron and Louis Richer and Suzanne Veillette and Daniel Gaudet and Tom{\'a}s Paus},
  journal={Hypertension},
  year={2010},
  volume={55 3},
  pages={706-14}
}
Intra-abdominal accumulation of fat is a hallmark of male body-fat distribution and a major risk factor for hypertension. Sympathoactivation may be one of the mechanisms linking intra-abdominal obesity to hypertension. The aim of the present study was to investigate whether a functional variation in the androgen-receptor gene (AR, a variable number of CAG repeats in exon 1) is associated with intra-abdominal adiposity, sympathetic modulation of vasomotor tone, and blood pressure in adolescent… CONTINUE READING