Functional ultrasound imaging of brain activity in human newborns

  title={Functional ultrasound imaging of brain activity in human newborns},
  author={Charlie Demen{\'e} and J{\'e}rome Baranger and M. Miron Bernal and Catherine Delanoe and St{\'e}phane Auvin and Valerie Biran and Marianne Alison and J{\'e}rome Mairesse and Elisabeth Harribaud and Mathieu Pernot and Micka{\"e}l Tanter and Olivier Baud},
  journal={Science Translational Medicine},
Functional neuroimaging modalities are crucial for understanding brain function, but their clinical use is challenging. Recently, the use of ultrasonic plane waves transmitted at ultrafast frame rates was shown to allow for the spatiotemporal identification of brain activation through neurovascular coupling in rodents. Using a customized flexible and noninvasive headmount, we demonstrate in human neonates that real-time functional ultrasound imaging (fUSI) is feasible by combining simultaneous… CONTINUE READING


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