Functional subcellular distribution of β1- and β2-adrenergic receptors in rat ventricular cardiac myocytes

@inproceedings{Cros2013FunctionalSD,
  title={Functional subcellular distribution of β1- and β2-adrenergic receptors in rat ventricular cardiac myocytes},
  author={Caroline Cros and Fabien Brette},
  booktitle={Physiological reports},
  year={2013}
}
β-adrenergic stimulation is a key regulator of cardiac function. The localization of major cardiac adrenergic receptors (β1 and β2) has been investigated using biochemical and biophysical approaches and has led to contradictory results. This study investigates the functional subcellular localization of β1- and β2-adrenergic receptors in rat ventricular myocytes using a physiological approach. Ventricular myocytes were isolated from the hearts of rat and detubulated using formamide… CONTINUE READING

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