Functional studies of nerve projections in the canine intestine.

  title={Functional studies of nerve projections in the canine intestine.},
  author={Edwin E. Daniel and F Kostolanska},
  journal={Canadian journal of physiology and pharmacology},
  volume={67 9},
An in vivo model has been developed to study nerve connections in the canine intestine, using spread of field stimulated contractions recorded proximally and distally with strain gauges and local intra-arterial injections of drugs. Excitation spread orally for several centimetres, more effectively at lower frequencies of field stimulation. This excitation was blocked by local hexamethonium or by a combination of atropine and naloxone (each of which reduced the contractions). Distal excitation… CONTINUE READING