Functional studies of Drosophila zinc transporters reveal the mechanism for zinc excretion in Malpighian tubules

@inproceedings{Yin2017FunctionalSO,
  title={Functional studies of Drosophila zinc transporters reveal the mechanism for zinc excretion in Malpighian tubules},
  author={Sai Yin and Qiuhong Qin and Bing Zhou},
  booktitle={BMC Biology},
  year={2017}
}
Zinc is an essential metal involved in many physiological processes. Previous work has identified a set of zinc transporters involved in Drosophila dietary zinc absorption. However, zinc excretion and reabsorption, the other two important processes to maintain zinc homeostasis, are not as well understood. In this work, we screened all the potential zinc transporter Zip (SLC39) and ZnT (SLC30) members for their likely roles in zinc excretion in Malpighian tubules, an insect organ functionally… CONTINUE READING