Functional structure of the organ of Corti: a review

@article{Lim1986FunctionalSO,
  title={Functional structure of the organ of Corti: a review},
  author={D. Lim},
  journal={Hearing Research},
  year={1986},
  volume={22},
  pages={117-146}
}
  • D. Lim
  • Published 1986
  • Medicine, Biology
  • Hearing Research
The mammalian auditory organs have a dual sensory system (inner vs. outer hair cells) with distinctly different cellular organizations and innervation patterns. However, the inner (IHCs) and outer (OHCs) hair cells are mechanoreceptors sharing similar general characteristics such as organization of stereocilia (including linkage system) and a gradation of stereociliary height along the length of the cochlea. This gradation of stereociliary height may be the single most important anatomic… Expand
Structural Organization of the Mammalian Auditory Hair Cells in Relation to Micromechanics
The mammalian auditory sensory cells are mechano-receptors characterized by sensory stereocilia, the cuticular plate, and the polarized cell body, innervated by the afferent and efferent nerveExpand
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The cytoskeleton of sensory hair cells is of particular interest since it is likely to affect the characteristics of mechano-electrical transduction in the cochlea, either indirectly, by maintainingExpand
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TLDR
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The stereociliary bundles of hair cells from the basilar papilla of the red-eared turtle were examined with transmission and high resolution scanning electron microscopy to provide a description ofExpand
Tectorial membrane-organ of Corti relationship during cochlear development
TLDR
The idea that although some structures, such as hair cells' stereocilia and innervation, are already formed early during development, the cochlear microarchitecture is not fully developed morphologically and ready to function normally until the end of the second postnatal week in the mouse is supported. Expand
The ultrastructure of the sensory hairs of the paratympanic organ receptor cells in chicken
TLDR
The study shows that the general conformation of the hair bundle and the stereociliary links of thehair cells in the paratympanic organ of chicken are similar to those previously described in the hair cells of the acoustico lateralis system. Expand
Auditory primary afferents in the starling: Correlation of function and morphology
  • O. Gleich
  • Medicine, Biology
  • Hearing Research
  • 1989
TLDR
Functional similarities between the respective hair cell populations of the hearing organs of birds and mammals are demonstrated by tracing the peripheral origin of functionally-characterized primary neurons. Expand
The Dimensions and Composition of Stereociliary Rootlets in Mammalian Cochlear Hair Cells: Comparison between High- and Low-Frequency Cells and Evidence for a Connection to the Lateral Membrane
TLDR
The structure and dimensions of rootlets relative to the stereocilia in apical and basal regions of rodent cochleae using light and electron microscopy suggest that rootlets strengthen the ankle region to provide durability and may contact with the lateral wall either to give additional anchoring of the stereOCilia or to provide a route for interactions between the bundle and theateral wall. Expand
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References

SHOWING 1-10 OF 93 REFERENCES
The ultrastructure of the organ of Corti.
  • R. Kimura
  • Biology, Medicine
  • International review of cytology
  • 1975
TLDR
This chapter discusses the ultrastructure of the organ of Corti with special emphasis on mechanoreceptors and neural elements, which is specially designed to convert mechanical vibrations into electrical events which are transmitted to the central nervous system as coded messages. Expand
Cochlear anatomy related to cochlear micromechanics. A review.
  • D. Lim
  • Chemistry, Medicine
  • The Journal of the Acoustical Society of America
  • 1980
TLDR
The sensory cilia of the mammalian cochlea show an orderly gradation in height and the relationship between the tectorial membrane and the slope of the reticular lamina along the length of the coChlea suggests that there may be additional mechanical fine-tuning capability built into the organ of Corti besides the basilar membrane. Expand
The sensory hairs and the tectorial membrane in the development of the cat s organ of Corti. A scanning electron microscopic study.
TLDR
The surface topography of the organ of Corti has been studied by scanning electron microscopy and the relationship between the outer margin of the tectorial membrane and the epithelial surface has been investigated. Expand
Hairs of the cochlear sensory cells and their attachment to the tectorial membrane.
  • R. Kimura
  • Biology, Medicine
  • Acta oto-laryngologica
  • 1966
TLDR
Modified cilia and numerous short hairs or microvilli were demonstrated at the base of the W in the sensory cells of the undifferentiated organ of Corti, but were lacking in the specimens of older animals. Expand
Morphological Basis of Directional Sensitivity of the Outer Hair Cells in the Organ of Corti
Electron‐microscope studies of cross sections of hair bundles on the outer hair cells in the organ of Corti show a consistent orientation of the sensory hairs. In the cuticle, a basal body isExpand
Cross-links between stereocilia in the guinea pig organ of Corti, and their possible relation to sensory transduction
TLDR
Hair cells of the guinea pig cochlea were preserved by fixing in glutaraldehyde without the use of osmium to explain the V shape of the rows of stereocilia on outer hair cells, and a membrane roughness was seen, particularly pronounced in the region of the stereocilium which gives rise to the cross-links. Expand
Absence of myosin-like immunoreactivity in stereocilia of cochlear hair cells
TLDR
In semi-thin, transverse sections of quick-frozen, freeze-dried and plastic-embedded guinea pig organ of Corti, myosin-like immunostaining was restricted to the apical cytoplasm of hair cells and was not detected along the stereocilia. Expand
Actin filaments, stereocilia, and hair cells of the bird cochlea. I. Length, number, width, and distribution of stereocilia of each hair cell are related to the position of the hair cell on the cochlea
TLDR
Because of the precision with which individual hair cells regulate the length, width, number, and distribution of their cell extensions, this stereocilia has a magnificent object with which to ask questions about how actin filaments that are present within the cell are regulated. Expand
Fine morphology of the tectorial membrane. Its relationship to the organ of Corti.
  • D. Lim
  • Biology, Medicine
  • Archives of otolaryngology
  • 1972
TLDR
Tectorial membranes of humans and animals were examined with the scanning and transmission electron microscopes and found Hensen's stripe, also found on the undersurface of the membrane near the inner hair cells, is morphologically similar to the marginal complex. Expand
Calcium-binding sites on sensory processes in vertebrate hair cells.
  • D. Moran, J. Rowley, D. Asher
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1981
TLDR
Electro-microscopic localization of calcium-binding sites on the sensory processes of vertebrate hair cells is described and calcium- and iron-containing deposits in the region of the ciliary necklace in goldfish lateral line hair cells are observed. Expand
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