• Corpus ID: 35888863

Functional states of RNA polymerase in the macronucleus of Tetrahymena pyriformis and their dependence on culture growth.

@article{Freiburg1981FunctionalSO,
  title={Functional states of RNA polymerase in the macronucleus of Tetrahymena pyriformis and their dependence on culture growth.},
  author={Manfred Freiburg},
  journal={Journal of cell science},
  year={1981},
  volume={47},
  pages={
          267-75
        }
}
  • M. Freiburg
  • Published 1 February 1981
  • Biology
  • Journal of cell science
RNA polymerase In in macronuclei of late log-phase cells of the ciliate Tetrahymena pyriformis is found to be present in 2 functional states, the one being actively engaged in transcription of ribosomal genes, the other one in a "free" state, i.e. free to transcribe added DNA or poly d(AT). Stimulation of RNA synthesis induced by dilution of stationary-phase cells into fresh medium is correlated with an increase in activity of template engaged and a decrease of free RNA polymerase I. In… 
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Results Citations
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References

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Evidence of a density-dependent inhibition of culture growth would indicate principles of growth control functioning in a similar way in unicellular organisms as observed in epithelial cells.
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