Functional similarities of microRNAs across different types of tissue stem cells in aging

@inproceedings{Watanabe2018FunctionalSO,
  title={Functional similarities of microRNAs across different types of tissue stem cells in aging},
  author={Koichiro Watanabe and Yasuaki Ikuno and Yumi Kakeya and Hirotaka Kito and Aoi Matsubara and Mizuki Kaneda and Yu Katsuyama and Hayato Naka-Kaneda},
  booktitle={Inflammation and regeneration},
  year={2018}
}
Restoration of tissue homeostasis by controlling stem cell aging is a promising therapeutic approach for geriatric disorders. The molecular mechanisms underlying age-related dysfunctions of specific types of adult tissue stem cells (TSCs) have been studied, and various microRNAs were recently reported to be involved. However, the central roles of microRNAs in stem cell aging remain unclear. Interest in this area was sparked by murine heterochronic parabiosis experiments, which demonstrated that… CONTINUE READING
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