Functional significance of the effects of neurotransmitters on the Na+,K+-ATPase system.

@article{Kometiani1984FunctionalSO,
  title={Functional significance of the effects of neurotransmitters on the Na+,K+-ATPase system.},
  author={Z P Kometiani and L G Tsakadze and Jariashvili TYa},
  journal={Journal of neurochemistry},
  year={1984},
  volume={42 5},
  pages={1246-50}
}
The aim of the present experiments was to study the effects of the neurotransmitters acetylcholine, noradrenaline, 5-hydroxytryptamine, and dopamine on the Na+,K+-ATPase of rat brain synaptosomal fractions. It is shown that dopamine at low concentrations specifically inhibits the Na+,K+-ATPase of synaptic membranes from the brain regions rich in dopaminergic endings, but has no effect on the synaptosomal Na+,K+-ATPase from the other parts of brain. Acetylcholine and noradrenaline have similar… CONTINUE READING

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