Functional significance of neuronal and extraneuronal transmitter uptake in rat salivary glands

@article{Almgren1974FunctionalSO,
  title={Functional significance of neuronal and extraneuronal transmitter uptake in rat salivary glands},
  author={Olle Almgren and Jan Jonason},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={1974},
  volume={283},
  pages={1-20}
}
The effect of normetanephrine (NM) on effector cell response to noradrenaline (NA) in vivo and on extraneuronal amine uptake in vitro has been investigated in rat submaxillayr glands. Tissue slices were incubated with 3H-NA and the metabolic pattern of the radioactivity in the slices as well as of the efflux from the slices was analyzed. The level of extraneuronally retained radioactive material was found to be markedly reduced at a NM concentration of 20 μg/ml after inhibition of neuronal… CONTINUE READING

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