Functional signatures of protective antiviral T-cell immunity in human virus infections.

@article{Harari2006FunctionalSO,
  title={Functional signatures of protective antiviral T-cell immunity in human virus infections.},
  author={Alexandre Harari and Val{\'e}rie Dutoit and Cristina Cellerai and P. Bart and Renaud A Du Pasquier and Giuseppe Pantaleo},
  journal={Immunological reviews},
  year={2006},
  volume={211},
  pages={
          236-54
        }
}
The most common human viruses have different abilities to establish persistent chronic infection. Virus-specific T-cell responses are critical in the control of virus replication and in the prevention of disease in chronic infection. A large number of phenotypic markers and a series of functions have been used to characterize virus-specific CD4+ and CD8+ T-cell responses, and these studies have shown great phenotypic and functional heterogeneity of the T-cell responses against different viruses… CONTINUE READING
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