Functional self-assembling peptide nanofiber hydrogel for peripheral nerve regeneration

@inproceedings{Wu2017FunctionalSP,
  title={Functional self-assembling peptide nanofiber hydrogel for peripheral nerve regeneration},
  author={Xiaoli Wu and Liumin He and Wen Jung Li and Heng Li and Wai-Man Wong and Seeram Ramakrishna and Wutian Wu},
  booktitle={Regenerative biomaterials},
  year={2017}
}
Peripheral nerves are fragile and easily damaged, usually resulting in nervous tissue loss, motor and sensory function loss. Advances in neuroscience and engineering have been significantly contributing to bridge the damage nerve and create permissive environment for axonal regrowth across lesions. We have successfully designed two self-assembling peptides by modifying RADA 16-I with two functional motifs IKVAV and RGD. Nanofiber hydrogel formed when combing the two neutral solutions together… CONTINUE READING
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