Functional roles of the tegument proteins of herpes simplex virus type 1.

  title={Functional roles of the tegument proteins of herpes simplex virus type 1.},
  author={Barbara J Kelly and Cornel Fraefel and Anthony L Cunningham and Russell J Diefenbach},
  journal={Virus research},
  volume={145 2},
Herpes virions consist of four morphologically distinct structures, a DNA core, capsid, tegument, and envelope. Tegument occupies the space between the nucleocapsid (capsid containing DNA core) and the envelope. A combination of genetic, biochemical and proteomic analysis of alphaherpes virions suggest the tegument contains in the order of 20 viral proteins. Historically the tegument has been described as amorphous but increasing evidence suggests there is an ordered addition of tegument during… CONTINUE READING


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