Functional roles of sialylation in breast cancer progression through miR-26a/26b targeting ST8SIA4

@inproceedings{Ma2016FunctionalRO,
  title={Functional roles of sialylation in breast cancer progression through miR-26a/26b targeting ST8SIA4},
  author={Xiaolu Ma and Weijie Dong and Zhen Su and Lifen Zhao and Y. Z. Miao and Nana Li and Huimin Zhou and Li Jia},
  booktitle={Cell Death and Disease},
  year={2016}
}
Sialylation is one of the altered glycosylation patterns associated with cancer progression. In this study, we investigated the N-glycan profiles of breast cancer patients and cell lines to reveal sialylation associated with breast cancer progression, and provided new evidences of miRNA-mediated sialylation. MALDI-TOF MS analysis revealed that N-glycans found in breast cancer tissues and breast cancer cell MDA-MB-231 featured increased levels of sialylation compared with adjacent tissues and… CONTINUE READING
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