Functional roles of short sequence motifs in the endocytosis of membrane receptors.

  title={Functional roles of short sequence motifs in the endocytosis of membrane receptors.},
  author={Kailash N. Pandey},
  journal={Frontiers in bioscience},
  • K. Pandey
  • Published 1 June 2009
  • Biology, Computer Science
  • Frontiers in bioscience
Internalization and trafficking of cell-surface membrane receptors and proteins into subcellular compartments is mediated by specific short-sequence signal motifs, which are usually located within the cytoplasmic domains of these receptor and protein molecules. The signals usually consist of short linear amino acid sequences, which are recognized by adaptor coat proteins along the endocytic and sorting pathways. The complex arrays of signals and recognition proteins ensure the dynamic movement… 

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