Functional roles of presynaptic GABA(A) receptors on glycinergic nerve terminals in the rat spinal cord.

@article{Jang2002FunctionalRO,
  title={Functional roles of presynaptic GABA(A) receptors on glycinergic nerve terminals in the rat spinal cord.},
  author={I S Jang and Hyo-Jin Jeong and Shutaro Katsurabayashi and Norio Akaike},
  journal={The Journal of physiology},
  year={2002},
  volume={541 Pt 2},
  pages={423-34}
}
GABA(A) receptor-mediated presynaptic depolarization is believed to induce presynaptic inhibition of excitatory synaptic transmission. We report here the functional roles of presynaptic GABA(A) receptors in glycinergic transmission of the rat spinal cord. In mechanically dissociated rat sacral dorsal commissural nucleus (SDCN) neurons attached with native glycinergic and GABAergic nerve terminals, glycinergic spontaneous inhibitory postsynaptic currents (sIPSCs) were isolated from a mixture of… CONTINUE READING

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