Functional roles of chromosomes 11 and 17 in the transformation of human breast epithelial cells in vitro.

Abstract

Genomic alterations in primary breast cancer play a role in the initiation and progression of the disease. We have analyzed the molecular events involved in the initiation and progression of the neoplastic process in an in vitro experimental system. Immortalization of human breast epithelial cells (HBEC) is associated with 3:9 translocation, p53 mutation… (More)

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@article{Yang1999FunctionalRO, title={Functional roles of chromosomes 11 and 17 in the transformation of human breast epithelial cells in vitro.}, author={Xiaofang Yang and Quivo Tahin and Y. F. Hu and Irene Russo and Binaifer R. Balsara and Doina Mihăilă and C. Slater and J Christian Barrett and John Russo}, journal={International journal of oncology}, year={1999}, volume={15 4}, pages={629-38} }