Functional roles of Ca(v)1.3, Ca(v)3.1 and HCN channels in automaticity of mouse atrioventricular cells: insights into the atrioventricular pacemaker mechanism.

@article{Marger2011FunctionalRO,
  title={Functional roles of Ca(v)1.3, Ca(v)3.1 and HCN channels in automaticity of mouse atrioventricular cells: insights into the atrioventricular pacemaker mechanism.},
  author={Laurine Marger and Pietro Mesirca and Jacqueline Alig and Angelo Giovanni Torrente and Stefan J Dubel and Birgit Engeland and Sandra Kanani and Pierre Fontanaud and J{\"o}rg Striessnig and Hee-sup Shin and Dirk Isbrandt and Heimo Ehmke and Jo{\"e}l Nargeot and Matteo E Mangoni},
  journal={Channels},
  year={2011},
  volume={5 3},
  pages={251-61}
}
The atrioventricular node controls cardiac impulse conduction and generates pacemaker activity in case of failure of the sino-atrial node. Understanding the mechanisms of atrioventricular automaticity is important for managing human pathologies of heart rate and conduction. However, the physiology of atrioventricular automaticity is still poorly understood… CONTINUE READING