Functional roles for the glutamines within the glutamine-rich region of the transcription factor sigma 54.

Abstract

Single and multiple point mutations were introduced to change the 12 glutamine residues within a 37-amino acid region of sigma 54. Multiple changes are shown to be required in order to interfere significantly with the function of this protein which is associated with enhancer-dependent bacterial transcription. Mutation of the central 4 glutamines leads to… (More)

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@article{Hsieh1994FunctionalRF, title={Functional roles for the glutamines within the glutamine-rich region of the transcription factor sigma 54.}, author={Mei Chin Hsieh and Yin Tintut and J. D. Gralla}, journal={The Journal of biological chemistry}, year={1994}, volume={269 1}, pages={373-8} }