Functional role of metaplastic paneth cell defensins in Helicobacter pylori-infected stomach.

BACKGROUND AND AIMS Chronic gastritis is caused by Helicobacter pylori infection, and gastritis is classified as inflammation, atrophy, and intestinal metaplasia. Detailed pathologic studies have shown that H. pylori settles on the surface of gastric mucosa, and that it is eliminated from metaplastic mucosa. However, its mechanism of natural protection is… CONTINUE READING