Functional role of calcium signals for microglial function.

  title={Functional role of calcium signals for microglial function.},
  author={Katrin Făerber and Helmut Kettenmann},
  volume={54 7},
In this review we summarize mechanisms of Ca(2+) signaling in microglial cells and the impact of Ca(2+) signaling and Ca(2+) levels on microglial function. So far, Ca(2+) signaling has been only characterized in cultured microglia and thus these data refer rather to activated microglia as observed in pathology when compared with the resting form found under physiological conditions. Purinergic receptors are the most prominently expressed ligand-gated Ca(2+)-permeable channels in microglia and… CONTINUE READING


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