Functional role of autophagy in gastric cancer

@inproceedings{Qian2016FunctionalRO,
  title={Functional role of autophagy in gastric cancer},
  author={Hao-ran Qian and Yi Yang},
  booktitle={Oncotarget},
  year={2016}
}
Autophagy is a highly regulated catabolic pathway responsible for the degradation of long-lived proteins and damaged intracellular organelles. Perturbations in autophagy are found in gastric cancer. In host gastric cells, autophagy can be induced by Helicobacter pylori (or H. pylori) infection, which is associated with the oncogenesis of gastric cancer. In gastric cancer cells, autophagy has both pro-survival and pro-death functions in determining cell fate. Besides, autophagy modulates gastric… CONTINUE READING
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