Functional relevance of antiemetic control. Experience using the FLIE questionnaire in a randomised study of the NK-1 antagonist aprepitant.

@article{Martin2003FunctionalRO,
  title={Functional relevance of antiemetic control. Experience using the FLIE questionnaire in a randomised study of the NK-1 antagonist aprepitant.},
  author={Allison R Martin and Alexandra D. Carides and Jay D Pearson and Kerry Horgan and Mark Elmer and Carrie M Schmidt and Bing Cai and Sant P. Chawla and Steven M. Grunberg},
  journal={European journal of cancer},
  year={2003},
  volume={39 10},
  pages={1395-401}
}
Little information exists on the functional impact of effective antiemetic protection. In the present study, the Functional Living Index-Emesis (FLIE), was used to assess patient-reported impact of chemotherapy-induced nausea and vomiting (CINV) after administration of a new NK-1 receptor antagonist (aprepitant). Cisplatin-treated patients in a double-blind randomised trial received either aprepitant+dexamethasone+ondansetron on day 1 and aprepitant+dexamethasone on days 2-5 or standard… CONTINUE READING

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