Functional properties of the unc-64 gene encoding a Caenorhabditis elegans syntaxin.

@article{Ogawa1998FunctionalPO,
  title={Functional properties of the unc-64 gene encoding a Caenorhabditis elegans syntaxin.},
  author={Hideoki Ogawa and Shoji Harada and Takeshi Sassa and Hiromitsu Yamamoto and Ryuji Hosono},
  journal={The Journal of biological chemistry},
  year={1998},
  volume={273 4},
  pages={2192-8}
}
Phenotypes of Caenorhabditis elegans unc-18 and unc-64 gene mutations are similar. While unc-18 is known to be essential for normal synaptic transmission (Hosono, R., Hekimi, S., Kamiya, Y., Sassa, T., Murakami, S., Nishiwaki, S., Miwa, J., Taketo, A., and Kodaira, K.-I. (1992) J. Neurochem. 58, 1517-1525), the function of unc-64 remains unclear. Here we describe the cloning, and the molecular and genetic characterization of the unc-64 gene, especially in relation to unc-18. unc-64 encodes a… CONTINUE READING