Functional properties of channels formed by the neuronal gap junction protein connexin36.

  title={Functional properties of channels formed by the neuronal gap junction protein connexin36.},
  author={Miduturu Srinivas and Renato Rozental and Takuro Kojima and Rolf Dermietzel and Mark F. Mehler and Daniele Filippo Condorelli and John A Kessler and David Conover Spray},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={19 22},
The expression and functional properties of connexin36 (Cx36) were examined in two communication-deficient cell lines (N2A-neuroblastoma and PC-12 cells) transfected with Cx36 and in hippocampal neurons that express the connexin endogenously. Transfected cells expressed the expected 2.9 kb Cx36 transcript and Cx36 immunoreactivity, whereas nontransfected cells were devoid of Cx36. The relationship between steady-state junctional conductance (g(j)) and transjunctional voltage was well described… CONTINUE READING
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