Functional polymorphisms of Monocyte Chemoattractant Protein-1 gene and Pott's disease risk.

Abstract

OBJECTIVE Monocyte Chemoattractant Protein-1 (MCP-1/CCL2), a key player in immune-mediated responses against Mycobacterium tuberculosis, is encoded by a polymorphic gene. Functionally relevant polymorphic variations in the MCP-1 gene have been associated with both susceptibility to and protection against tuberculosis-related disorders. Here, we investigated… (More)
DOI: 10.1016/j.imbio.2015.11.004

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