Functional polymorphism in the GPR55 gene is associated with anorexia nervosa.

@article{Ishiguro2011FunctionalPI,
  title={Functional polymorphism in the GPR55 gene is associated with anorexia nervosa.},
  author={Hiroki Ishiguro and Emmanuel S. Onaivi and Yasue Horiuchi and Keiko Imai and Gen Komaki and Toshio Kariya Ishikawa and Mari Suzuki and Yuichiro Watanabe and Tetsuya Ando and Susumu Higuchi and Tadao Arinami},
  journal={Synapse},
  year={2011},
  volume={65 2},
  pages={
          103-8
        }
}
Endocannabinoids, anandamide, and 2-arachidonoyl glycerol are involved in food intake and appetite. Although anandamide is now thought to be a ligand for vanilloid receptor, receptors that are targets of anandamide could play a similar role in eating behaviors and related disorders. This study therefore focused on the receptor, which is called G-protein-coupled receptor 55 (GPR55) that had recently been reported to have binding affinity for endocannabinoids. Functional analysis of the sole… CONTINUE READING

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