Functional phenotyping and genotyping of circulating tumor cells from patients with castration resistant prostate cancer.

Abstract

Circulating tumor cells (CTCs) hold promise for studying advanced prostate cancer. A functional collagen adhesion matrix (CAM) assay was used to enrich CTCs from prostate cancer patients' blood. CAM ingestion and epithelial immuno-staining identified CTCs, which were genotyped using oligonucleotide array comparative genomic hybridization. The highest CTC… (More)
DOI: 10.1016/j.canlet.2008.12.007

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