Functional overexpression of genes involved in erythritol synthesis in the yeast Yarrowia lipolytica

  title={Functional overexpression of genes involved in erythritol synthesis in the yeast Yarrowia lipolytica},
  author={Aleksandra M Mirończuk and Anna Biegalska and Adam Dobrowolski},
  booktitle={Biotechnology for biofuels},
BACKGROUND Erythritol, a four-carbon polyol synthesized by microorganisms as an osmoprotectant, is a natural sweetener produced on an industrial scale for decades. Despite the fact that the yeast Yarrowia lipolytica has been reported since the 1970s as an erythritol producer, the metabolic pathway of this polyol has never been characterized. It was shown that erythritol synthesis in yeast occurs via the pentose phosphate pathway (PPP). The oleaginous yeast Y. lipolytica is a good host for… CONTINUE READING
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