Functional overexpression and characterization of lipogenesis-related genes in the oleaginous yeast Yarrowia lipolytica

@article{Silverman2016FunctionalOA,
  title={Functional overexpression and characterization of lipogenesis-related genes in the oleaginous yeast Yarrowia lipolytica},
  author={Andrew M. Silverman and Kangjian Qiao and Peng Xu and Gregory Stephanopoulos},
  journal={Applied Microbiology and Biotechnology},
  year={2016},
  volume={100},
  pages={3781-3798}
}
Single cell oil (SCO) is an attractive energy source due to scalability, utilization of low-cost renewable feedstocks, and type of product(s) made. Engineering strains capable of producing high lipid titers and yields is crucial to the economic viability of these processes. However, lipid synthesis in cells is a complex phenomenon subject to multiple layers of regulation, making gene target identification a challenging task. In this study, we aimed to identify genes in the oleaginous yeast… CONTINUE READING
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