Functional organization of the basal ganglia: Therapeutic implications for Parkinson's disease

  title={Functional organization of the basal ganglia: Therapeutic implications for Parkinson's disease},
  author={Jose A. Obeso and Maria C. Rodriguez-Oroz and Beatriz Ben{\'i}tez-Temi{\~n}o and Franscisco J. Blesa and Jorge Guridi and Concepci{\'o} Mar{\'i}n and Manuel Rodriguez},
  journal={Movement Disorders},
The basal ganglia (BG) are a highly organized network, where different parts are activated for specific functions and circumstances. The BG are involved in movement control, as well as associative learning, planning, working memory, and emotion. We concentrate on the “motor circuit” because it is the best understood anatomically and physiologically, and because Parkinson's disease is mainly thought to be a movement disorder. Normal function of the BG requires fine tuning of neuronal… 
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