Functional organization of the basal ganglia: Therapeutic implications for Parkinson's disease

@article{Obeso2008FunctionalOO,
  title={Functional organization of the basal ganglia: Therapeutic implications for Parkinson's disease},
  author={J. Obeso and M. Rodriguez-Oroz and B. Ben{\'i}tez-Temi{\~n}o and F. J. Blesa and J. Guridi and C. Mar{\'i}n and Manuel Rodriguez},
  journal={Movement Disorders},
  year={2008},
  volume={23}
}
The basal ganglia (BG) are a highly organized network, where different parts are activated for specific functions and circumstances. The BG are involved in movement control, as well as associative learning, planning, working memory, and emotion. We concentrate on the “motor circuit” because it is the best understood anatomically and physiologically, and because Parkinson's disease is mainly thought to be a movement disorder. Normal function of the BG requires fine tuning of neuronal… Expand

Paper Mentions

Observational Clinical Trial
Parkinson's disease is the second most common neurodegenerative disease affecting about 1-3% of population above 60 years. Recently, non-motor symptoms are getting more attention in PD… Expand
ConditionsParkinson's Disease
Functional neuroanatomy of the basal ganglia.
Changing Views of Basal Ganglia Circuits and Circuit Disorders
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References

SHOWING 1-10 OF 129 REFERENCES
The functions of the basal ganglia and the paradox of stereotaxic surgery in Parkinson's disease.
A new dynamic model of the cortico-basal ganglia loop.
  • A. Nambu
  • Biology, Medicine
  • Progress in brain research
  • 2004
The Basal Ganglia in Human Learning
  • C. Seger
  • Psychology, Medicine
  • The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry
  • 2006
The functional anatomy of basal ganglia disorders
Multiple output channels in the basal ganglia.
Metabolic effects of nigrostriatal denervation in basal ganglia
Basal ganglia and cerebellar loops: motor and cognitive circuits
...
1
2
3
4
5
...