Functional neurogenesis in the adult hippocampus

@article{Praag2002FunctionalNI,
  title={Functional neurogenesis in the adult hippocampus},
  author={Henriette van Praag and Alejandro F Schinder and Brian R Christie and Nicolas Toni and Theo D. Palmer and Fred H. Gage},
  journal={Nature},
  year={2002},
  volume={415},
  pages={1030-1034}
}
There is extensive evidence indicating that new neurons are generated in the dentate gyrus of the adult mammalian hippocampus, a region of the brain that is important for learning and memory. However, it is not known whether these new neurons become functional, as the methods used to study adult neurogenesis are limited to fixed tissue. We use here a retroviral vector expressing green fluorescent protein that only labels dividing cells, and that can be visualized in live hippocampal slices. We… CONTINUE READING
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