Functional neuroanatomy of thyroid hormone feedback in the human hypothalamus and pituitary gland
@article{Fliers2006FunctionalNO, title={Functional neuroanatomy of thyroid hormone feedback in the human hypothalamus and pituitary gland}, author={E. Fliers and U. Unmehopa and A. Alkemade}, journal={Molecular and Cellular Endocrinology}, year={2006}, volume={251}, pages={1-8} }
A major change in thyroid setpoint regulation occurs in various clinical conditions such as critical illness and psychiatric disorders. As a first step towards identifying determinants of these setpoint changes, we have studied the distribution and expression of thyroid hormone receptor (TR) isoforms, type 2 and type 3 deiodinase (D2 and D3), and the thyroid hormone transporter monocarboxylate transporter 8 (MCT8) in the human hypothalamus and anterior pituitary. Although the post-mortem… CONTINUE READING
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