Functional modules of sigma factor regulons guarantee adaptability and evolvability.

@article{Binder2016FunctionalMO,
  title={Functional modules of sigma factor regulons guarantee adaptability and evolvability.},
  author={Sebastian C. Binder and Denitsa Eckweiler and Sebastian Schulz and Agata Bielecka and Tanja Nicolai and Raimo Franke and S. H{\"a}u\ssler and Michael Meyer-Hermann},
  journal={Scientific reports},
  year={2016},
  volume={6},
  pages={22212}
}
The focus of modern molecular biology turns from assigning functions to individual genes towards understanding the expression and regulation of complex sets of molecules. Here, we provide evidence that alternative sigma factor regulons in the pathogen Pseudomonas aeruginosa largely represent insulated functional modules which provide a critical level of… CONTINUE READING