Functional modulation of ligand-gated GABAA and NMDA receptor channels by phosphorylation.

  title={Functional modulation of ligand-gated GABAA and NMDA receptor channels by phosphorylation.},
  author={Erwin Sigel},
  journal={Journal of receptor and signal transduction research},
  volume={15 1-4},
  • Erwin Sigel
  • Published 1995 in
    Journal of receptor and signal transduction…
Ion channels are ubiquitous membrane proteins that may be organized into different families according to their predicted transmembrane topology. They are concerned with rapid signalling over plasma and intracellular membranes and are activated, depending on their type, by transmembrane voltage, intracellular second messengers or extracellular neurotransmitters. Intracellular activities of protein kinases and phosphatases act to modulate ion channel activity. The modulation of the function of… CONTINUE READING


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